These are data from one of the first successful trials of adjuvant chemotherapy for colon cancer. Levamisole is a low-toxicity compound previously used to treat worm infestations in animals; 5-FU is a moderately toxic (as these things go) chemotherapy agent. There are only one record per patient for the death outcome (or censoring). This is redistributed from the survival package, with a small modification to include only the death outcome.

colon

Format

A data frame with 929 rows and 17 variables:

id

id

study

1 for all patients

rx

Treatment - Obs(ervation), Lev(amisole), Lev(amisole)+5-FU

sex

1=male

age

in years

obstruct

obstruction of colon by tumour

perfor

perforation of colon

adhere

adherence to nearby organs

nodes

number of lymph nodes with detectable cancer

time

days until death or censoring

status

censoring status

differ

differentiation of tumour (1=well, 2=moderate, 3=poor)

extent

Extent of local spread (1=submucosa, 2=muscle, 3=serosa, 4=contiguous structures)

surg

time from surgery to registration (0=short, 1=long)

node4

more than 4 positive lymph nodes

etype

event type: 1=recurrence,2=death

event

event indicator: censored, death

See also