Computes the standardized total gain for the risk difference. Optionally produces bootstrap standard errors and confidence intervals. The standardized total gain is the area between the risk difference curve and the horizontal line at the marginal risk difference. If the outcome is time to event then the STG is time-dependent, and a time point for evaluation is needed. If one is not provided then the restricted mean survival is estimated from the data and used.
Usage
calc_STG(
psdesign,
t,
sig.level = 0.05,
n.samps = 5000,
bootstraps = TRUE,
permute = TRUE,
permute.times = 2000,
progress.bar = TRUE
)Arguments
- psdesign
A psdesign object. It must contain a risk model, an integration model, and estimated parameters. Bootstrapped parameters are optional
- t
For time to event outcomes, a fixed time
tmay be provided to compute the cumulative distribution function. If not, the restricted mean survival time is used. Omit for binary outcomes.- sig.level
Significance level for bootstrap confidence intervals
- n.samps
The number of samples to take over the range of S.1 at which the VE is calculated
- bootstraps
If true, and bootstrapped estimates are present, will calculate bootstrap standard errors and confidence interval.
- permute
Not used, included for backwards compatibility
- permute.times
Not used, included for backwards compatibility
- progress.bar
Not used, included for backwards compatibility